Concomitant administration of promethazine products with other respiratory depressants has an Affiliation with respiratory melancholy, and at times Loss of life, in pediatric patients. promethazine decreases effects of pitolisant by Other (see remark). Steer clear of or Use Alternate Drug. Remark: Pitolisant increases histamine stages during the Mind; thus, H1 https://wockusa.com/product/ocaliva-obeticholic-acid/