Butabarbital will lower the level or outcome of fedratinib by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Stay away from or Use Alternate Drug. Effect of coadministering a robust CYP3A4 inducer with fedratinib has not been analyzed. butabarbital will lower the extent or effect of fosphenytoin by impacting hepatic enzyme CYP2C9/10 metabolism. https://tinac184jkj2.wikimidpoint.com/user